•Favipiravir is a novel antiviral drug now in clinical trials for the treatment of influenza.
•It acts as a pseudo purine nucleic acid in virus-infected cells.
•Favipiravir inhibits the RNA polymerase of many different RNA viruses.
•It blocks replication of many strains of influenza virus, including the H7N9 avian virus.
•Favipiravir is also active against many arena-, bunya-, flavi-, alpha-, picorna- and noroviruses.
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